Wrap in Vigor Regenerating your creatures is generally worse than granting indestructible, if only because a handful of wraths like Damnation ignore it
Just look at the capability with Magistrate's Scepter, Lux Cannon, and Darksteel Reactor onboard the spacecraft commander
Basically, if your commander is a Shaman, Warlock, or Wizard and has blue in its color identity, I think youre going to want to run this
Its more skill-intensive, since it feels worse to bin a spell than tuck it on the bottom of your deck (even though the two are often functionally equivalent)
It is a powerful stalemate breaker, a solid threat, good value and good utility all rolled into one
Aether Vial 4/10 This is yet another non-threat card that becomes pretty weak beyond the first couple of turns