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S)-AHPC-CO-C5-acid Synonyms CAS Number 2162120-87-6 Related CAS Molecular Formula C29H40N4O6S Molecular Weight 572
The methyl group is inert in this context and cannot undergo the nucleophilic substitution reaction that the chloroalkane relies on to bind the HaloTag protein
Product Name DOTA-C2-maleimide Synonyms CAS Number 1006711-90-5 Related CAS Molecular Formula C22H34N6O9 Molecular Weight 526
5-ROX is the purified single isomer of 5(6)-ROX
Hormone Receptor-Positive
Azide-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg S)-AHPC-CO-C5-acid Synonyms CAS Number 2162120-87-6SOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC
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