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MC-Val-Cit-PAB(m-PEG8)-Exatecan cp Product Name Pomalidomide-5'-C4-amine HCl Synonyms

SKU: 39906041668

4.1
USD495.00 USD534.00

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Description

Product Name Pomalidomide-5'-C4-amine HCl Synonyms CAS Number n/a Related CAS 1957236-35-9 (free base) Molecular Formula C17H21ClN4O4 Molecular Weight 380

a transcription factor implicated in Duane Radial Ray syndrome

31 SMILES FC(F)(F)C1=CC(SC2=C(Cl)C=CC=C2Cl)=C(C(=O)N2CC3=CC=CC(C#N)=C3C2)C(=O)N1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

Product Name Lenalidomide-acetamido-O-PEG2-C2-Cl Synonyms Lenalidomide-4'-acetamido-O-PEG2-C2-Cl CAS Number n/a Related CAS Molecular Formula C21H26ClN3O7 Molecular Weight 467

Product Name 1-Chloro-4-(methoxy-d3)naphthalene Synonyms CAS Number n/a Related CAS Molecular Formula C11H9ClO Molecular Weight 195

MC-Val-Cit-PAB(m-PEG8)-Exatecan cp Product Name Pomalidomide-5'-C4-amine HCl SynonymsSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,

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