Lenalidomide-6'-bromide thalidomide Allele-selective lowering of mutant HTT

Allele-selective lowering of mutant HTT protein by HTT–LC3 linker compounds

281 SMILES BrCCCCCC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

S)-AHPC-CO-C9-acid Synonyms CAS Number 2172819-78-0 Related CAS Molecular Formula C33H48N4O6S Molecular Weight 628

Product Name Thalidomide-O-acetamido-C6-OH Synonyms Thalidomide-4'-O-acetamido-C6-OH CAS Number n/a Related CAS Molecular Formula C21H25N3O7 Molecular Weight 431

383 SMILES OCCOCCCC1=CC=C2C(CN(C3CCC(=O)NC3=O)C2=O)=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Lenalidomide-6'-bromide thalidomide Allele-selective lowering of mutant HTTDegrader building block for targeted protein degradation. Contains an E3 ligase ligand with a linker and a function group, which can be conjugated to target protein ligands through straightforward chemical reactions. Product Name Lenalidomide 6' bromide Synonyms CAS Number n a Related CAS Molecular Formula C13H11BrN2O3 Molecular Weight 323. 146 SMILES BrC1=CC=C2CN(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature