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Propargyl-Acetyl-Val-Ala-PAB(m-PEG8)-MMAE Size:10mg Chloroquinaxoline sulfonamide (CQS) promotes the

SKU: 44202758036

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Description

Chloroquinaxoline sulfonamide (CQS) promotes the recruitment of RBM39 (RNA binding motif protein 39) to the CUL4-DCAF15 E3 ubiquitin ligase for degadation

This enables researchers to visualize and track proteins or other cellular structures with minimal background interference

445 SMILES OCCCCCCNC(=O)COC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

527 SMILES [N-]=[N+]=NCCOCCOCCOCCOCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

CA-SS-BODIPY is a cleavable HaloTag ligand featuring a disulfide bond that can be cleaved using a reducing agent

Propargyl-Acetyl-Val-Ala-PAB(m-PEG8)-MMAE Size:10mg Chloroquinaxoline sulfonamide (CQS) promotes theSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing

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