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dual-color imaging enables the distinction between misfolded oligomers and insoluble aggregates in live cells
Product Name Phthalimidinoglutarimide-5'-C7-OH Synonyms CAS Number n/a Related CAS Molecular Formula C20H26N2O4 Molecular Weight 358
NCCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
188 Purity (HPLC) >= 95% Solubility DMSO
the chloro atom in Biotin-PEG4-halo is replaced with a methyl group
DBCO-Propionyl-Val-Ala-PAB(m-PEG8)-MMAE Size:10mg dual-color imaging enables the distinctionSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing
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