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Product Name Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Synonyms CAS Number Related CAS Molecular Formula C62H95N11O25 Molecular Weight 1394
Chloroquinaxoline sulfonamide (CQS) are aryl sulfonamides with anticancer activity
148 Purity (HPLC) >= 95% Solubility DMSO
The Val–Cit dipeptide is optimized for cathepsin B cleavage in lysosomal environments
which uses copper(I) to accelerate the reaction between a terminal alkyne and an azide
Mal-Acetyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE Fluorescent Product Name Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-PNP Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload
