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Product Name DOTA-tris(t-Bu)ester-C3-propanamido-maleimide Synonyms CAS Number n/a Related CAS Molecular Formula C38H65N7O10 Molecular Weight 779
Product Name Pomalidomide-5'-PEG3-C2-amine HCl Synonyms CAS Number n/a Related CAS 1957236-37-1 (free base) Molecular Formula C21H29ClN4O7 Molecular Weight 484
452 SMILES NCCN1CCN(CCN2CCN(CCN)CC2)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Linker substitution influences succinimide ring hydrolysis equilibrium impacting the stability of attachment to antibody-drug conjugates
NCCCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Fmoc-Val-Ala-PAB(m-PEG8)-PNP Size:10mg Product Name DOTA-tris(t-Bu)ester-C3-propanamido-maleimide Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be finely tuned
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