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DBCO-Dap(m-PEG4)-Val-Cit-PAB m-peg8 644 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCOCC#C)CCN(CC(O)=O)CC1 Purity (HPLC)

SKU: 65314115144

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Description

644 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCOCC#C)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

97 SMILES Cl

Its active site reacts with chloroalkane substrates to form an irreversible bond

Product Name Mal-Propionyl-PEG6-Val-Ala-PAB(m-PEG4)-PNP Synonyms CAS Number Related CAS Molecular Formula C54H79N7O22 Molecular Weight 1178

Product Name Mal-Propionyl-Dap(m-PEG4)-Val-Ala-PAB(m-PEG4)-MMAE Synonyms CAS Number Related CAS Molecular Formula C85H136N12O25 Molecular Weight 1726

DBCO-Dap(m-PEG4)-Val-Cit-PAB m-peg8 644 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCOCC#C)CCN(CC(O)=O)CC1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG,

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