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Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG8)-PNP Size:100mg 07 SMILES CC(C)C(N(CCCN)C(=O)C1=CC=C(C)C=C1)C1=NC2=CC(Cl)=CC=C2C(=O)N1CC1=CC=CC=C1 Purity (HPLC)

SKU: 70410055243

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Description

07 SMILES CC(C)C(N(CCCN)C(=O)C1=CC=C(C)C=C1)C1=NC2=CC(Cl)=CC=C2C(=O)N1CC1=CC=CC=C1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

Product Name Thalidomide-O-PEG5-propargyl Synonyms Thalidomide-4'-O-PEG5-propargyl CAS Number 2411681-90-6 Related CAS Molecular Formula C26H32N2O10 Molecular Weight 532

SulfoCy5-CA CAS Number Related CAS Molecular Formula C43H60ClN3O9S2 Molecular Weight 862

Product Name Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG8)-PNP Synonyms CAS Number Related CAS Molecular Formula C58H87N7O24 Molecular Weight 1266

Product Name DOTA-tris(t-Bu)ester-C6-amine Synonyms CAS Number n/a Related CAS Molecular Formula C34H66N6O7 Molecular Weight 670

Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG8)-PNP Size:100mg 07 SMILES CC(C)C(N(CCCN)C(=O)C1=CC=C(C)C=C1)C1=NC2=CC(Cl)=CC=C2C(=O)N1CC1=CC=CC=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating

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