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Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE dacf1 Fmoc-Val-Cit-PAB is a cleavable ADC

SKU: 70899872356

4.7
USD495.00 USD545.00

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Description

Fmoc-Val-Cit-PAB is a cleavable ADC linker featuring a Val–Cit dipeptide and a para-aminobenzyl (PAB) spacer

Product Name Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C51H87N7O19 Molecular Weight 1102

197 Purity (HPLC) >= 95% Solubility DMSO

497 SMILES OCCOCCOCCOCCOCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

CA-SS-SiR is a cleavable HaloTag ligand featuring a disulfide bond that can be cleaved using a reducing agent

Azide-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-MMAE dacf1 Fmoc-Val-Cit-PAB is a cleavable ADCSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Azide Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further

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