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Mal-Propionyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE dacf1 Anticancer sulfonamides target splicing by

SKU: 78873390867

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Description

Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15

Product Name Pomalidomide-5'-C2-OH Synonyms CAS Number n/a Related CAS Molecular Formula C15H15N3O5 Molecular Weight 317

5-FAM cadaverine is an excellent building block to prepare fluorescent ligands for receptor binding assays

Product Name Thalidomide-5'-O-PEG2-C2-azide Synonyms CAS Number 2640388-57-2 Related CAS Molecular Formula C19H21N5O7 Molecular Weight 431

This makes it ideal for high-resolution imaging techniques like STED (Stimulated Emission Depletion) and SIM (Structured Illumination Microscopy)

Mal-Propionyl-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE dacf1 Anticancer sulfonamides target splicing bySOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The

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