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Mal-Acetyl-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-Exatecan Biotin 6-SiR-CA CAS Number Related CAS

SKU: 81518537679

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Description

6-SiR-CA CAS Number Related CAS Molecular Formula C37H48ClN3O5Si Molecular Weight 678

Product Name Mal-Propionyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-PNP Synonyms CAS Number Related CAS Molecular Formula C50H71N7O20 Molecular Weight 1090

454 SMILES OC(=O)CCOCCOCCOCCOC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

497 SMILES OCCOCCOCCOCCOCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name CA-SiR Synonyms SiR-Halo

Mal-Acetyl-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-Exatecan Biotin 6-SiR-CA CAS Number Related CASSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan,

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