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DBCO-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan Size:1mg Product Name Thalidomide-5'-O-PEG2-C2-acid Synonyms CAS

SKU: 84836984913

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Description

Product Name Thalidomide-5'-O-PEG2-C2-acid Synonyms CAS Number 2682112-08-7 Related CAS Molecular Formula C20H22N2O9 Molecular Weight 434

Product Name DOTA-PEG6-propargyl Synonyms CAS Number n/a Related CAS Molecular Formula C31H55N5O13 Molecular Weight 705

613 Purity (HPLC) >= 95% Solubility DMSO

S)-AHPC-acetamido-O-PEG3-propargyl Synonyms CAS Number 2098799-81-4 Related CAS Molecular Formula C33H46N4O8S Molecular Weight 658

Product Name ispinesib Synonyms 8F20

DBCO-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan Size:1mg Product Name Thalidomide-5'-O-PEG2-C2-acid Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC

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