Propargyl-Gly(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan pab Nitrogen Heterocycle Based Linker (NHBL)

Nitrogen Heterocycle Based Linker (NHBL)

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2-d3)acetyl]phenyl}acetamide Synonyms CAS Number n/a Related CAS Molecular Formula C10H11NO2 Molecular Weight 180

Product Name Pomalidomide-C6-OH Synonyms Pomalidomide-4'-C6-OH CAS Number 2140807-30-1 Related CAS Molecular Formula C19H23N3O5 Molecular Weight 373

338 SMILES OC(=O)CCC(=O)NC1=CC=C2C(CN(C3CCC(=O)NC3=O)C2=O)=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Propargyl-Gly(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan pab Nitrogen Heterocycle Based Linker (NHBL)SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous