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such as the copper-catalyzed azide-alkyne cycloaddition (CuAAC) and the strain-promoted alkyne-azide cycloaddition (SPAAC)
Product Name DOTA-propargyl Synonyms CAS Number n/a Related CAS Molecular Formula C19H31N5O7 Molecular Weight 441
thus all the instrument settings of the ROX conjugates would be applicable to the applications of ROX alkyne conjugates
BCN reacts efficiently with azides to form stable 1
31 SMILES FC(F)(F)C1=CC(SC2=C(Cl)C=CC=C2Cl)=C(C(=O)N2CC3=CC=CC(C#N)=C3C2)C(=O)N1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO
Mal-Propionyl-Dap(m-PEG4)-Val-Ala-OH ptotac ligand such as the copper-catalyzed azide-alkyneSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine
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