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Mal-Propionyl-PEG6-Val-Cit-PAB(m-PEG4) Size:10mg good photostability

SKU: 89830262428

4.7
USD195.00 USD240.00

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Description

good photostability

Rational discovery of molecular glue degraders via scalable chemical profiling

72 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCN=[N+]=[N-])C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

thus has excellent cell permeability

Product Name Thalidomide-O-PEG3-C2-Cl Synonyms Thalidomide-4'-O-PEG3-C2-Cl CAS Number n/a Related CAS Molecular Formula C21H25ClN2O8 Molecular Weight 468

Mal-Propionyl-PEG6-Val-Cit-PAB(m-PEG4) Size:10mg good photostabilitySOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG6 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX

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