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It reduces mHTT levels through autophagic degradation by interacting with both the autophagosome protein microtubule-associated protein 1A/1B light chain 3 (LC3)1 and mutant huntingtin protein (mHTT)
and cell-permeable
A general strategy to develop cell permeable and fluorogenic probes for multicolour nanoscopy
Product Name Pomalidomide-5'-C2-OH Synonyms CAS Number n/a Related CAS Molecular Formula C15H15N3O5 Molecular Weight 317
Cy3 (Cyanine 3
DBCO-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan Size:25mg It reduces mHTT levels throughSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to
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