Mal-Propionyl-Dap(m-PEG4)-Val-Ala-PAB(m-PEG4)-PNP Size:25mg Product Name Thalidomide-O-PEG5-OH Synonyms Thalidomide-4'-O-PEG5-OH

Product Name Thalidomide-O-PEG5-OH Synonyms Thalidomide-4'-O-PEG5-OH CAS Number 2484091-02-1 Related CAS Molecular Formula C23H30N2O10 Molecular Weight 494

653 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

68 SMILES Cl

Product Name tert-butyl 2-{4-[(piperidin-4-yl)methyl]piperazin-1-yl}acetate Synonyms CAS Number n/a Related CAS Molecular Formula C16H31N3O2 Molecular Weight 297

Product Name DOTA-tris(t-Bu)ester-PEG2-C2-azide Synonyms CAS Number n/a Related CAS Molecular Formula C34H64N8O9 Molecular Weight 728

Mal-Propionyl-Dap(m-PEG4)-Val-Ala-PAB(m-PEG4)-PNP Size:25mg Product Name Thalidomide-O-PEG5-OH Synonyms Thalidomide-4'-O-PEG5-OHSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The PNP (para