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Azide-Hexanoyl-Val-Cit-PAB(m-PEG8)-MMAE Size:5mg 443 SMILES CC(C)(C)OC(=O)CN1CCN(CC2CCNCC2)CC1 Purity (HPLC)

SKU: 95641465082

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Description

443 SMILES CC(C)(C)OC(=O)CN1CCN(CC2CCNCC2)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

S)-AHPC-acetamido-O-PEG6-C1-acid Synonyms CAS Number n/a Related CAS Molecular Formula C38H58N4O13S Molecular Weight 810

Product Name Pomalidomide-C4-acid Synonyms Pomalidomide-4'-C4-acid CAS Number 2225940-48-5 Related CAS Molecular Formula C18H19N3O6 Molecular Weight 373

Product Name BG-DBCO Synonyms SNAP-DBCO CAS Number 1820756-74-8  Related CAS Molecular Formula C32H27N7O3 Molecular Weight 557

Trametinib binds KRS-MEK and disrupts RAF-MEK

Azide-Hexanoyl-Val-Cit-PAB(m-PEG8)-MMAE Size:5mg 443 SMILES CC(C)(C)OC(=O)CN1CCN(CC2CCNCC2)CC1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing

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