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Azide-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan deuterium-labeled-ketone Product Name Thalidomide-5'-alkyne-C4-OH Synonyms CAS

SKU: 96130969989

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Description

Product Name Thalidomide-5'-alkyne-C4-OH Synonyms CAS Number n/a Related CAS Molecular Formula C19H18N2O5 Molecular Weight 354

89 SMILES: CCN(CC)C1=CC=C2C(OC3=CC(C=CC3=C2C2=CC=C(C=C2S([O-])(=O)=O)S(=O)(=O)NCCOCCOCCOCC#C)=[N+](CC)CC)=C1 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

Product Name MC-Val-Cit-PAB(m-PEG4)-PNP Synonyms CAS Number Related CAS Molecular Formula C45H62N8O16 Molecular Weight 971

CA-SulfoCy5 is a HaloTag ligand with SulfoCyanine5 dye

Product Name DBCO-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C83H102FN9O20 Molecular Weight 1564

Azide-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan deuterium-labeled-ketone Product Name Thalidomide-5'-alkyne-C4-OH Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC

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