Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG4) Size:100mg Product Name CC-220 Synonyms Iberdomide

Product Name CC-220 Synonyms Iberdomide CAS Number 1323403-33-3 Related CAS Molecular Formula C25H27N3O5 Molecular Weight 449

S)-AHPC-acetamido-O-PEG1-C1-acid Synonyms CAS Number 2172820-08-3 Related CAS Molecular Formula C28H38N4O8S Molecular Weight 590

89 SMILES ClCCOCCOCCOCC(=O)NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

7 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCOCCN=[N+]=[N-])C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

1039/d3md00569k

Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG4) Size:100mg Product Name CC-220 Synonyms IberdomideSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. Derived