Quoting thegamer, the cards are are selected based on their gameplay and story value, and in particular how each character relates to the overall narrative of the set
The three sets are Secret Lair x Final Fantasy: Game Over, Secret Lair x Final Fantasy : Grimoire, and Secret Lair x Final Fantasy : Weapons
The new Detective cards are the core of the strategy considering almost all their abilities target or require another Detective card in play
The Constructed players, or people who don't have much time to draft, are usually good with the second milestone
The goal of the game is to be the first player to gather 20 lore, with players able to gain lore by exhausting their character cards on the table
You do not need a character at a location to gain the lore, it simply occurs at the start of each turn