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19(9):576-91
TNF promotes the inflammatory responses that often lead to autoimmune disorders such as rheumatoid arthritis
Amino Acid Sequence
(1997) An antagonist decoy receptor and a death domain-containing receptor for TRAIL
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Human TNFR2 Mouse IgG2a Wildtype Fc Amount:10 mg 19(9):576-91TNFR2 is a single pass type I membrane protein and the member of TNFR superfamily containing 4 cysteine rich domains (CRD) repeats. In addition to the full length membrane anchored form, soluble TNFR2 can be generated via two distinct mechanisms: (1) shedding via proteolytic processing of the full membrane anchored from, and (2) translation from an alternatively spliced message encoding the extracellular domains of TNFR2. Interacting protein(s): TNF
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