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Daidzein is a natural isoflavone phytoestrogen found in Leguminosae
6 nM and 3
Ruxolitinib (INCB018424) is the first potent
>130-fold selectivity for JAK1/2 versus JAK3
used in the treatment of some forms of osteoporosis
SAR131675 Heavy Duty Daidzein is a natural isoflavoneSAR131675 is a VEGFR3 inhibitor with IC50 Ki of 23 nM 12 nM in cell free assays, about 50 and 10 fold more selective for VEGFR3 than VEGFR1 2, little activity against Akt1, CDKs, PLK1, EGFR, IGF 1R, c Met, Flt2 etc.
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