The Binding of Isaac Four Souls Second Edition 111 Note: insert designed for game

Note: insert designed for game with external box dimensions of 22

to protect your own spaces from attack

they flip the removed tiles to their opposite side — from white to black — and place them in the newly empty spots

Just like in Ticket to Ride

The Root board game is required to play

The Binding of Isaac Four Souls Second Edition 111 Note: insert designed for gameThe official Binding of Isaac multiplayer card game, about sacrifice, betrayal and hoarding. 2 4 players take turns playing loot cards and using items to kill monsters that yield more items, loot, and sometimes souls. The first player to end their turn with 4 souls is the winner. Cooperation, barter, and betrayal is encouraged.